Guo, Jing published the artcileVisible-Light Catalyzed [1+2+2] Cycloaddition Reactions Enabled by the Formation of Methylene Nitrones, Safety of 4-Methoxyphenylacetic acid, the main research area is isoxazolidine preparation photochem; nitroarene alkene dimethylaniline cycloaddition iridium photocatalyst; aryl glycine alkene nitroarene cycloaddition iridium photocatalyst.
Herein, the first photo-redox synthesis of methylene nitrone intermediates from nitroarenes and arylamines were reported. The highly reactive methylene nitrones were in situ trapped by alkenes to afford various isoxazolidines. This three-component reaction features the use of N,N-dimethylanilines or N-aryl glycines as C1 building blocks, which allow for the one-pot formal [1+2+2] cycloaddition from simple starting materials. A wide range of useful isoxazolidines can be obtained under mild conditions with moderate to good yields. Mechanistic investigations supported the formation of methylene nitrone via selective N-CH3 bond cleavage and methylene transfer.
Advanced Synthesis & Catalysis published new progress about [2+2+1] Cycloaddition reaction. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Safety of 4-Methoxyphenylacetic acid.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem