Suzuki, Hirotsugu published the artcileRhodium-catalysed decarbonylative C(sp2)-H alkylation of indolines with alkyl carboxylic acids and carboxylic anhydrides under redox-neutral conditions, HPLC of Formula: 104-01-8, the main research area is pyrimidinyl indoline preparation; indoline carboxylic acid decarbonylative alkylation catalyst rhodium; anhydride carboxylic indoline decarbonylative alkylation catalyst rhodium.
A rhodium-catalyzed decarbonylative C(sp2)-H alkylation method for indolines was developed. This reaction facilitated the use of alkyl carboxylic acids and their anhydrides as a cheap, abundant and non-toxic alkyl source under redox-neutral conditions, featuring the introduction of a primary alkyl chain, which cannot be addressed by previous radical-mediated decarboxylative reaction. Through a mechanistic investigation, revealed that an initially formed C-7 acylated indoline was transformed into the corresponding alkylated indoline I [R1 = H, 2-Me, 3-Me, 2-Ph; R2 = 4-Me, 5-Me, 5-MeO, etc.; R3 = Me, i-Bu, cyclohexyl, etc.] via a decarbonylation process.
Organic & Biomolecular Chemistry published new progress about Alkylation (decarbonylative). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, HPLC of Formula: 104-01-8.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem