Ahmad, Wasi Md. published the artcilePotential dual imaging nanoparticle: Gd2O3 nanoparticle, Recommanded Product: Diatrizoic Acid, the main research area is prostate cancer gadolinium oxide nanoparticle MRI CT cytotoxicity theragnosis.
Gadolinium (Gd) is a unique and powerful element in chem. and biomedicine which can be applied simultaneously to magnetic resonance imaging (MRI), X-ray computed tomog. (CT), and neutron capture therapy for cancers. This multifunctionality can be maximized using gadolinium oxide (Gd2O3) nanoparticles (GNPs) because of the large amount of Gd per GNP, making both diagnosis and therapy (i.e., theragnosis) for cancers possible using only GNPs. In this study, the T1 MRI and CT dual imaging capability of GNPs is explored by synthesizing various iodine compound (IC) coated GNPs (IC-GNPs). All the IC-GNP samples showed stronger X-ray absorption and larger longitudinal water proton relaxivities (r1 = 26-38 s-1mM-1 and r2/r1 = 1.4-1.9) than the resp. com. contrast agents. In vivo T1 MR and CT images of mice were also acquired, supporting that the GNP is a potential dual imaging agent.
Scientific Reports published new progress about Absorption (X-ray). 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Recommanded Product: Diatrizoic Acid.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem