Theansungnoen, Tinnakorn’s team published research in Cosmetics in 2022 | CAS: 598-50-5

Cosmetics published new progress about Anti-aging agents. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, HPLC of Formula: 598-50-5.

Theansungnoen, Tinnakorn published the artcilePhytochemical Analysis and Antioxidant, Antimicrobial, and Antiaging Activities of Ethanolic Seed Extracts of Four Mucuna Species, HPLC of Formula: 598-50-5, the main research area is Mucuna seed extract phytochem analysis antioxidant antimicrobial antiaging activity.

The investigation into promising botanical materials for natural cosmetics is expanding due to environmental and health awareness. Here, we aimed to evaluate the phytochem. substances and the potential skin-related pharmacol. activities of four Mucuna seeds, namely M. gigantea (Willd.) DC. (MGG), M. interrupta Gagnep. (MIT), M. monosperma Wight (MMM), and M. pruriens (L.) DC. (MPR), belonging to the Fabaceae family. In methodol., the Mucuna seeds were authenticated using morphol. and mol. approaches. L-DOPA, phenolics, and flavonoid content, incorporated with HPLC and GC-MS fingerprinting analyses, were determined Then, skin-related antimicrobial, antioxidant, and antiaging activities were determined The results revealed that MPR showed the highest L-DOPA content (75.94 mg/100 mg extract), whereas MGG exhibited the highest phenolic and flavonoid content (56.73 ± 0.62 mg gallic/g extract and 1030.11 ± 3.97 mg quercetin/g extract, resp.). Only MMM and MPR could inhibit all of S. aureus, S. epidermidis, and C. albicans, but no sample could inhibit C. acnes. Furthermore, all samples demonstrated antioxidant activity. Interestingly, all Mucuna samples exhibited strong collagenase, elastase, and hyaluronidase inhibitory activities. We conclude that the ethanolic extracts of four Mucuna seeds are probably advantageous in the development of skincare cosmeceutical products.

Cosmetics published new progress about Anti-aging agents. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, HPLC of Formula: 598-50-5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem