Elliott, J. J. et al. published their research in Journal of the Chemical Society in 1959 | CAS: 23707-37-1

Isoquinolin-7-amine (cas: 23707-37-1) belongs to isoquinoline derivatives. Being an analog of pyridine, isoquinoline is a weak base, with a pKa of 5.14. They are also used to make oil-soluble dyes, food colorants, pharmaceuticals, pH indicators and other organic compounds. HPLC of Formula: 23707-37-1

Heats and entropies of ionization of some aromatic and N-heteroaromatic amines was written by Elliott, J. J.;Mason, S. F.. And the article was included in Journal of the Chemical Society in 1959.HPLC of Formula: 23707-37-1 This article mentions the following:

The ionization constants of a series of unsubstituted polycyclic aromatic amines were measured at 0 and 20° in 50% EtOH-H2O solution, and those of a series of N-heteroaromatic amines at 5 and 35° in H2O. Entropies and enthalpies of ionization were calculated The compounds studied were PhNH2; o-, m-, and p-NH2C6H4Ph; 2-aminofluorene; 1- and 2-naphthylamine; 1-, 2-, 3-, and 9-phenanthrylamine; 1-, 2-, and 9-anthrylamine; 3-aminopyrene; 2-, 3-, and 4-aminopyridine; 2-, 3-, 4-, 5-, 6-, 7-, and 8-aminoquinoline; 1-, 3-, 4-, 5-, 6-, 7-, and 8-aminoisoquinoline; 1-, 2-, 3-, 4-, and 5-aminoacridine; 6- and 9-aminophenanthridine; 2-amino-4-methyl-5,6-, 1′- and 4′-amino-5,6-, 3-amino-6,7-, and 2-amino-4-methyl-7,8-benzoquinoline; 8-amino-1,2-, and 8-amino-3,4-benzacridine. The variation in the ionization constants of the aromatic amines is due equally to the entropy and the enthalpy factor, whereas the variation in the N-heteroaromatic series is due primarily to enthalpy changes. The dissociation entropies of the conjugate acids of the periarom. amines are larger than those of the unhindered isomers, which in turn have larger values than those of the N-heteroaromatic amines. These results are discussed in relation to the solvation of the amine cations and the π-electron energy changes accompanying their dissociation In the experiment, the researchers used many compounds, for example, Isoquinolin-7-amine (cas: 23707-37-1HPLC of Formula: 23707-37-1).

Isoquinolin-7-amine (cas: 23707-37-1) belongs to isoquinoline derivatives. Being an analog of pyridine, isoquinoline is a weak base, with a pKa of 5.14. They are also used to make oil-soluble dyes, food colorants, pharmaceuticals, pH indicators and other organic compounds. HPLC of Formula: 23707-37-1

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem