Westaway, Susan M. et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2006 | CAS: 23707-37-1

Isoquinolin-7-amine (cas: 23707-37-1) belongs to isoquinoline derivatives. Quinoline and isoquinoline skeletons are among the most attractive frameworks with a wide range of biological and pharmacological activities. Most traditional methods of generating isoquinoline do so via oxidative aromatization of dihydro- or tetrahydro-isoquinolines, usually offering some environmental or economic advantage.Formula: C9H8N2

N-Tetrahydroquinolinyl, N-quinolinyl and N-isoquinolinyl biaryl carboxamides as antagonists of TRPV1 was written by Westaway, Susan M.;Chung, Ying-Kit;Davis, John B.;Holland, Vicky;Jerman, Jeffrey C.;Medhurst, Stephen J.;Rami, Harshad K.;Stemp, Geoffrey;Stevens, Alexander J.;Thompson, Mervyn;Winborn, Kim Y.;Wright, James. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2006.Formula: C9H8N2 This article mentions the following:

Starting from a high throughput screening hit, novel N-tetrahydroquinolinyl, N-quinolinyl and N-isoquinolinyl carboxamides have been identified as potent antagonists of the ion channel TRPV1. The N-quinolinylnicotinamide I showed excellent potency at human, guinea pig and rat TRPV1, a favorable in vitro DMPK profile and activity in an in vivo model of inflammatory pain. In the experiment, the researchers used many compounds, for example, Isoquinolin-7-amine (cas: 23707-37-1Formula: C9H8N2).

Isoquinolin-7-amine (cas: 23707-37-1) belongs to isoquinoline derivatives. Quinoline and isoquinoline skeletons are among the most attractive frameworks with a wide range of biological and pharmacological activities. Most traditional methods of generating isoquinoline do so via oxidative aromatization of dihydro- or tetrahydro-isoquinolines, usually offering some environmental or economic advantage.Formula: C9H8N2

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem