Jiang, Rong et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2007 | CAS: 23707-37-1

Isoquinolin-7-amine (cas: 23707-37-1) belongs to isoquinoline derivatives. Although isoquinoline derivatives can be synthesized by several methods, relatively few direct methods deliver the unsubstituted isoquinoline. The Pomeranz–Fritsch reaction provides a method for the preparation of isoquinoline. This reaction uses a benzaldehyde and aminoacetoaldehyde diethyl acetal, which in an acid medium react to form isoquinoline.Computed Properties of C9H8N2

3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors was written by Jiang, Rong;Duckett, Derek;Chen, Weiming;Habel, Jeff;Ling, Yuan Yuan;LoGrasso, Philip;Kamenecka, Theodore M.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2007.Computed Properties of C9H8N2 This article mentions the following:

The structure-based design and synthesis of a novel series of c-Jun N-terminal kinase (JNK) inhibitors with selectivity against p38 is reported. The unique structure of these 3,5-disubstituted quinolines, e.g. I, was developed from the previously reported 4-(2,7-phenanthrolin-9-yl)phenol. The X-ray crystal structure of I in JNK3 reveals an unexpected binding mode for this new scaffold with protein. In the experiment, the researchers used many compounds, for example, Isoquinolin-7-amine (cas: 23707-37-1Computed Properties of C9H8N2).

Isoquinolin-7-amine (cas: 23707-37-1) belongs to isoquinoline derivatives. Although isoquinoline derivatives can be synthesized by several methods, relatively few direct methods deliver the unsubstituted isoquinoline. The Pomeranz–Fritsch reaction provides a method for the preparation of isoquinoline. This reaction uses a benzaldehyde and aminoacetoaldehyde diethyl acetal, which in an acid medium react to form isoquinoline.Computed Properties of C9H8N2

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem