Palladium supported on metal-organic framework as a catalyst for the hydrogenation of nitroarenes under mild conditions was written by Bao, Lingxiang;Yu, Zongbao;Fei, Teng;Yan, Zhiyuan;Li, Jiazhe;Sun, Chenghui;Pang, Siping. And the article was included in Applied Organometallic Chemistry in 2020.Name: 5-Nitroisoquinoline This article mentions the following:
A highly active and selective metal-organic framework-supported palladium catalyst was prepared for synthesis of amines ArNH2 [Ar = Ph, 4-MeC6H4, 1-naphthyl, etc.] via catalytic hydrogenation of nitroarenes. High selectivity (>99%) and excellent yield (98%) of aniline were realized after 2 h in ethanol under hydrogen (1 atm) at room temperature The reductions were successfully carried out in presence of a wide range of other reducible functional groups. More importantly, the catalyst was very stable without loss of its catalytic activity after five cycles. In the experiment, the researchers used many compounds, for example, 5-Nitroisoquinoline (cas: 607-32-9Name: 5-Nitroisoquinoline).
5-Nitroisoquinoline (cas: 607-32-9) belongs to isoquinoline derivatives. Although isoquinoline derivatives can be synthesized by several methods, relatively few direct methods deliver the unsubstituted isoquinoline. The discovery of chloroquine, the most well-known drug containing this stent, has helped bring about decades of malaria control and treatment.Name: 5-Nitroisoquinoline
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem