147497-32-3, 6-Bromo-3,4-dihydroisoquinolin-1(2H)-one is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
b) Compound B (0.5 g, 2.21 mmol) was dissolved in dry DMF (3 mL) and 60% sodium hydride was added on ice bath(1.76 g, 4.42 mmol), stirred for 30 minutes, and added methyl 4-bromomethyl benzoate (0.557 g, 2.23 mmol).Stir at room temperature for 1 hour, pour into 100 mL crushed ice, extract with ethyl acetate (100 mL*3), combine the organic layers, and in turn water100 mL of 100 mL of saturated brine was extracted and dried over anhydrous sodium sulfate. The residue was purified by flash silica gel column chromatography usingElution with oleyl ether/ethyl acetate (V/V=5:1) gave compound C (0.74 g) as a pale yellow solid with a yield of 90%.
147497-32-3 6-Bromo-3,4-dihydroisoquinolin-1(2H)-one 21865450, aisoquinoline compound, is more and more widely used in various.
Reference£º
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Shen Jingkang; Xiong Bing; Zhao Lele; Li Jia; Geng Meiyu; Ma Lanping; Chen Danqi; Su Mingbo; Zhou Yubo; Hu Xiaobei; Liu Hongchun; Shen Aijun; (54 pag.)CN107879975; (2018); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem