630421-73-7,630421-73-7, 1,6-Dichloroisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stirred solution of 1 ,6-dichloroisoquinoline (500 mg, 2.56 mmol)DMSO (5 mL) at RT, piperazine-2-carboxamide (425.6 mg, 2.56 mmol) and K2C03 (1.05 g, 7.68 mmol). The reaction mixture was heated at 80C for 5 h. The reactionmixture was diluted with ethyl acetate and washed with brine. The organic layer was dried over anhydrous Na2SO4, filtered and concentrated in vacuo. The residue was purified by flash colunm chromatography on silica gel (ethyl acetate/petroleum ether1:5) to afford the desired product (80 mg, 12% yield). ESI-MS m/z: 291[M + H].
As the paragraph descriping shows that 630421-73-7 is playing an increasingly important role.
Reference£º
Patent; ARAXES PHARMA LLC; JANES, Matthew, Robert; PATRICELLI, Matthew, Peter; LI, Liansheng; REN, Pingda; LIU, Yi; (397 pag.)WO2016/44772; (2016); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem