1532-97-4, 4-Bromoisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
4-bromoisoquinoline (1) (1 g, 4.7 mmol) was treated with 4-formylphenylboronic acid (0.77 g, 5.17 mmol), Pd[PPh3]4 (0.27 g,0.235 mmol), K2CO3 (1.94 g, 14.1 mmol) in THF (50 ml) at 70 ¡ãC under nitrogen atmosphere for 12 h and progress of the reaction was monitored by TLC. The reaction mixture was quenched with water, extracted with CH2Cl2 and washed with brine (2 10 mL). The organic layer was separated, dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was purifiedby column chromatography (EtOAc/hexane) to afford pure 4-(isoquinolin-4-yl)benzaldehyde. The yields and important spectral data are given below.
1532-97-4, 1532-97-4 4-Bromoisoquinoline 73743, aisoquinoline compound, is more and more widely used in various fields.
Reference£º
Article; Nagarajan; Prakash, Asit; Velmurugan; Shakti, Nanda; Katiyar, Monica; Venuvanalingam; Renganathan; Dyes and Pigments; vol. 102; (2014); p. 180 – 188;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem