Cao, Zhu team published research on Green Chemistry in | 1532-97-4

Application In Synthesis of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Isoquinoline is a heterocyclic aromatic organic compound. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. Application In Synthesis of 1532-97-4.

Cao, Zhu;Ji, Meishan;Wang, Xinxin;Wu, Xinxin;Li, Yahong;Zhu, Chen research published 《 Metal-free photo-induced heteroarylations of C-H and C-C bonds of alcohols by flow chemistry》, the research content is summarized as follows. Practical, metal-free heteroarylations of C-H and C-C bonds of unprotected aliphatic alcs. ROH (R = 5-hydroxypentan-2-yl, 6-hydroxyhexan-3-yl, 5-hydroxy-2-methylpentan-2-yl, etc.) are accomplished in a ′stop-flow′ micro-tubing reactor. The reactions proceed through alkoxy radical-triggered hydrogen atom transfer and β-C(sp3)-C(sp3) bond rupture under mild photochem. conditions, leading to a plethora of valuable functionalized heteroarenes ArR (Ar = 4-chloroquinolin-2-yl, 4-methylquinolin-2-yl, quinazolin-4-yl, etc.). The reaction is amenable for late-stage functionalization of complex heteroarenes, and can be readily scaled up by a continuous-flow method. The protocol features many advantages including good regioselectivity, broad functional group compatibility, and easy operation, and may find potential use in medicinal chem.

Application In Synthesis of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem