In a broader sense, the term isoquinoline is used to make reference to isoquinoline derivatives. 1-Benzylisoquinoline is the structural backbone in naturally occurring alkaloids including papaverine. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. The isoquinoline ring in these natural compound derives from the aromatic amino acid tyrosine. Safety of 4-Bromoisoquinoline.
Song, Wenyue;Rao, Xiaofeng;Bu, Qingqing;Liu, Ning research published 《 Carbazole-bridged NCN-pincer palladium complex catalyzed direct C-H arylation reaction of azoles》, the research content is summarized as follows. A new type of pincer palladium complexes C1∼C6 based on the strong donor strength of carbazoles skeleton were synthesized. The air- and moisture-stable complexes C1∼C6 act as efficient catalysts for the direct arylation of azoles with (hetero)aryl bromides in good to excellent yields with broad substrate scope used KOAc as sole base under aerobic conditions. It was demonstrated that this developed protocol was used as catalytic system for the direct C-H bond arylation of thiazoles under relatively mild reaction conditions at a low catalyst loading of 0.5 mol%.
Safety of 4-Bromoisoquinoline, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.
4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem