Isoquinoline’s properties: Isoquinoline is a colorless hygroscopic liquid at temperatures above its melting point with a penetrating, 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. unpleasant odor. Impure samples can appear brownish, as is typical for nitrogen heterocycles. Name: 4-Bromoisoquinoline.
Zhang, Dong;Cai, Jinlin;Du, Jinze;Wang, Qingdong;Yang, Jinming;Geng, Rongqing;Fang, Zheng;Guo, Kai research published 《 Electrochemical-Oxidation-Promoted Direct N-ortho-Selective Difluoromethylation of Heterocyclic N-Oxides》, the research content is summarized as follows. An efficient and green electrochem. N-ortho-selective difluoromethylation method of various quinoline and isoquinoline N-oxides has been developed. In this method sodium difluoromethanesulfinate (HCF2SO2Na) was used as the source of difluoromethyl moiety and various N-ortho-selective difluoromethylation quinolines and isoquinolines N-oxides were obtained in good to excellent yield under constant current. In addition, the reaction was easy to scale up and maintains good yields. Preliminary mechanism studies suggested that the reaction has underwent a free radical addition and hydrogen elimination pathway.
Name: 4-Bromoisoquinoline, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.
4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem