Fuse, Hiromu; Irie, Yu; Fuki, Masaaki; Kobori, Yasuhiro; Kato, Kosaku; Yamakata, Akira; Higashi, Masahiro; Mitsunuma, Harunobu; Kanai, Motomu published the artcile< Identification of a Self-Photosensitizing Hydrogen Atom Transfer Organocatalyst System>, Product Details of C10H9NO, the main research area is aldehyde isoquinoline organocatalyst photochem hydroxyalkylation C H activation; isoquinolylmethanol preparation; alc isoquinoline organocatalyst photochem alkylation C H activation; alkylisoquinoline preparation.
Organocatalyst systems to promote the cleavage of stable C-H bonds, such as formyl, α-hydroxy and benzylic C-H bonds, through a hydrogen atom transfer (HAT) process without the use of exogenous photosensitizers have been developed. An electronically tuned thiophosphoric acid, 7,7′-OMe-TPA, were assembled with substrate or co-catalyst N-heteroaromatics through hydrogen bonding and π-π interactions to form electron donor-acceptor (EDA) complexes. Photoirradiation of the EDA complex induced stepwise, sequential single-electron transfer (SET) processes to generate a HAT-active thiyl radical. The first SET were from the electron-rich naphthyl group of 7,7′-OMe-TPA to the protonated N-heteroaromatics and the second proton-coupled SET (PCET) from the thiophosphoric acid moiety of 7,7′-OMe-TPA to the resulting naphthyl radical cation. Spectroscopic studies and theor. calculations characterized the stepwise SET process mediated by short-lived intermediates. This organocatalytic HAT system were applied to four different carbon-hydrogen (C-H) functionalization reactions, hydroxyalkylation and alkylation of N-heteroaromatics, acceptorless dehydrogenation of alcs. and benzylation of imines, with high functional group tolerance.
Journal of the American Chemical Society published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 90806-58-9 belongs to class isoquinoline, and the molecular formula is C10H9NO, Product Details of C10H9NO.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem