Li, Shasha; Pissarnitski, Dmitri; Nowak, Timothy; Wleklinski, Michael; Krska, Shane W. published the artcile< Merging Late-Stage Diversification with Solid-Phase Peptide Synthesis Enabled by High-Throughput On-Resin Reaction Screening>, HPLC of Formula: 721401-43-0, the main research area is solid phase peptide synthesis high throughput experimentation; Suzuki Miyaura coupling peptide boronic acid library.
An integrated workflow is described that combines micromole-scale high-throughput experimentation (HTE) reaction screening and solid-phase peptide synthesis (SPPS) to enable rapid synthetic method development for on-resin peptide diversification. Using this new approach, we have identified several sets of robust Suzuki-Miyaura coupling conditions with complementary scope that collectively display broad coverage with respect to both resin-bound peptide substrates containing aryl halide side chains and (hetero)arylboronic acid coupling partners. We have also demonstrated the utility of this integrated SPPS/chem. diversification method by synthesizing a multidimensional library of diverse peptides in high yields.
ACS Catalysis published new progress about Amino acids Role: CMB (Combinatorial Study), RCT (Reactant), RACT (Reactant or Reagent). 721401-43-0 belongs to class isoquinoline, and the molecular formula is C9H8BNO2, HPLC of Formula: 721401-43-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem