On July 28, 2022, Gu, Qiong; Xu, Jun; Fang, Yuying published a patent.Safety of 8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one The title of the patent was Process for preparation of benzimidazole compound and application thereof in preparation of ferroptosis inhibitor. And the patent contained the following:
The invention relates to preparation of a benzimidazole compound, and an application thereof in preparation of a ferroptosis inhibitor. The benzimidazole compound has a structure as shown in formula I or II. According to the benzimidazole compound provided by the present invention, a lipophilic group is introduced to an R1 position, and a specific group is introduced to an R2 position, such that the obtained compound has relatively good ferroptosis inhibitory activity and can be used as a lead compound for preventing and treating nervous system diseases such as stroke. The experimental process involved the reaction of 8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one(cas: 74904-29-3).Safety of 8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
The Article related to benzimidazole compound preparation ferroptosis inhibitory, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Safety of 8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem