Clare, Daniel published the artcileChemospecific Cyclizations of α-Carbonyl Sulfoxonium Ylides on Aryls and Heteroaryls, HPLC of Formula: 104-01-8, the main research area is chemospecific cyclization carbonyl sulfoxonium ylide aryl heteroaryl; safety advantage carbonyl sulfoxonium ylide; chemospecifity; cyclization; hexafluoroisopropanol; iridium; sulfoxonium.
The functionalization of aryl and heteroaryls using α-carbonyl sulfoxonium ylides without the help of a directing group has remained so far a neglected area, despite the advantageous safety profile of sulfoxonium ylides (safety: an α-diazo ketone was potentially explosive, whereas an α-carbonyl sulfoxonium ylide was not). Described herein are the cyclizations of α-carbonyl sulfoxonium ylides onto benzenes, benzofurans and N-p-toluenesulfonyl indoles in the presence of a base in HFIP [e.g., I â?II (91%) in presence of K2CO3 in HFIP], whereas pyrroles and N-Me indoles undergo cyclization in the presence of an iridium catalyst. Significantly, these two sets of conditions are chemospecific for each groups of substrates.
Angewandte Chemie, International Edition published new progress about Carbonyl compounds (organic), diazo Role: RCT (Reactant), RACT (Reactant or Reagent) (exothermic decomposition of α-diazo ketone vs. α-carbonyl sulfoxonium ylide). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, HPLC of Formula: 104-01-8.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem