Luo, Zhenli published the artcileMetal-Free Reductive Amination of Ketones with Amines Using Formic Acid as the Reductant under BF3 · Et2O Catalysis, Computed Properties of 5961-59-1, the main research area is ketone amine formic acid boron trifluoride etherate reductive amination; alkylamine preparation.
BF3·Et2O was found to effectively catalyze reductive amination of ketones with amines employing formic acid as the reductant under metal-free conditions. This transformation tolerated a broad range of primary and secondary amines and differently decorated ketones, delivering N-alkylated amines in good to excellent yields with high compatibility of functional groups. The synthetic potential of this protocol was demonstrated by its application in the preparation of biol. and pharmaceutically relevant compounds
Asian Journal of Organic Chemistry published new progress about Ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Computed Properties of 5961-59-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem