Yang, Xiao-Chao published the artcileAccess to Chiral 2,5-Pyrrolidinyl Dispirooxindoles via Dinuclear Zinc-Catalyzed Asymmetric Cascade Reactions, Name: 4-Methoxy-N-methylaniline, the main research area is amino oxindole keto amide diastereoselective enantioselective zinc azacrown ligand; pyrrolidinyl dispirooxindole stereoselective preparation; Michael cyclic keto imine formation Friedel Crafts cascade.
A series of new nonsym. semi-azacrown ether ligands were developed and applied to the asym. Michael/cyclic keto-imine formation/Friedel-Crafts alkylation reactions of 3-amino oxindole hydrochlorides and β,γ-unsaturated α-keto amides. A diversity of 2,5-pyrrolidinyl dispirooxindoles containing two nonadjacent spiro-quaternary stereocenters were obtained in excellent diastereoselectivities and moderate to excellent enantioselectivities (up to 95% ee). A possible catalytic cycle was proposed to explain the origin of the asym. induction.
Journal of Organic Chemistry published new progress about Azacrown ethers Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Name: 4-Methoxy-N-methylaniline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem