Boeldl, Marlene published the artcileDehydrative Coupling of Benzylic Alcohols Catalyzed by Bronsted Acid/Lewis Base, Application In Synthesis of 151-10-0, the main research area is olefin preparation diastereoselective; alc dehydrative coupling sulfonic acid triphenylphosphane catalyst; diaryl ethane preparation regioselective; benzylic alc arene dehydrative hydroarylation Bronsted acid catalyst.
A simple and direct, metal-free protocol for the synthesis of olefins (E)-4-R1-2-R2C6H3CH(Me)CH=CHC6H3-4-R1-2-R2 (R1 = H, Ph, Br, F, I, Cl, NO2, CF3, Me; R2 = H, Cl, Me) by applying catalytic amounts of a sulfonic acid and triphenylphosphane under air has been reported. A variety of olefins could be synthesized from benzylic alcs. 4-R1-2-R2C6H3CH(Me)OH under relatively mild conditions. Addnl., dehydrative hydroarylation of benzylic alcs. ArCH(OH)Me (Ar = 2-chlorophenyl, biphenyl-4-yl, 2-naphthyl, etc.) with electron-rich arenes 3,5-(MeO)2C6H3R3 (R3 = H, OMe) was possible by using only Bronsted acid under otherwise same reaction conditions. Here, it shows that phosphane additives are essential to overcome oligomerization as main side reaction by the occupancy of the reactive carbocation intermediate.
European Journal of Organic Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Application In Synthesis of 151-10-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem