Chahal, Mandeep K. published the artcileMolecular Engineering of β-Substituted Oxoporphyrinogens for Hydrogen-Bond Donor Catalysis, Computed Properties of 86-51-1, the main research area is mol engineering oxoporphyrinogen bifunctional organocatalyst hydrogen bond donor catalysis; conjugate addition oxoporphyrinogen organocatalyst; sulfa Michael oxoporphyrinogen organocatalyst; Henry oxoporphyrinogen organocatalyst; aza Henry oxoporphyrinogen organocatalyst.
A new class of bifunctional hydrogen-bond donor organocatalyst using oxoporphyrinogens having increased intramol. hydrogen-bond donor distances is reported. Oxoporphyrinogens are highly non-planar rigid macrocycles containing a multiple hydrogen bond-forming binding site. In this work, we describe the first example of non-planar OxPs as hydrogen-bond donor catalysts prepared using a mol. engineering approach of the binding site for dual activation of substrates. The introduction of β-substituents is key to the catalytic activity and the catalysts are able to catalyze 1,4-conjugate additions and sulfa-Michael additions, as well as, Henry and aza-Henry reactions at low catalyst loadings (â?1 mol-%) under mild conditions (e.g., catalyst I). Preliminary mechanistic studies have been carried out and a possible reaction mechanism has been proposed based on the bi-functional activation of both substrates through hydrogen-bonding interactions.
European Journal of Organic Chemistry published new progress about Alkylation (selective alkylation of oxoporphyrinogen aldehydes). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Computed Properties of 86-51-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem