Eisenreich, Fabian published the artcileDirect C-H Trifluoromethylation of (Hetero)Arenes in Water Enabled by Organic Photoredox-Active Amphiphilic Nanoparticles, Formula: C8H10O2, the main research area is amphiphilic polymer catalyst preparation recyclability; arene togni reagent polymer catalyst photochem regioselective trifluoromethylation; trifluoromethyl arene preparation green chem; enzyme mimics; green chemistry; nanoparticles; photoredox catalysis; trifluoromethylation.
It was shown that trifluoromethyl groups can be readily installed into a broad range of organic compounds by using water as the reaction medium and light as the energy source. To bypass solubility obstacles, robust water-soluble polymeric nanoparticles that accommodate reagents and photocatalysts within their hydrophobic interior under high local concns was developed. By taking advantage of the high excited state reduction potential of N-phenylphenothiazine (PTH) through UV light illumination, the direct C-H trifluoromethylation of a wide array of small organic mols. was achieved selectively with high substrate conversion. Key to the approach was slowing down the production of CF3 radicals during the chem. process by reducing the catalyst loading as well as the light intensity, thereby improving effectiveness and selectivity of this aqueous photocatalytic method. Furthermore, the catalyst system showed excellent recyclability and can be fueled by sunlight. The method proposed here is versatile, widely applicable, energy efficient, and attractive for late-stage introduction of trifluoromethyl groups into biol. active mols.
Chemistry – A European Journal published new progress about Green chemistry. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Formula: C8H10O2.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem