Kim, Yongtae’s team published research in Organic & Biomolecular Chemistry in 2019 | CAS: 151-10-0

Organic & Biomolecular Chemistry published new progress about Benzofurans Role: SPN (Synthetic Preparation), PREP (Preparation) (dihydro). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Product Details of C8H10O2.

Kim, Yongtae published the artcileFriedel-Crafts alkylation with α-bromoarylacetates for the preparation of enantioenriched 2,2-diarylethanols, Product Details of C8H10O2, the main research area is dihydrobenzofuran preparation; diarylethanol enantioselective regioselective preparation Mitsunobu; bromoarylacetate arene Friedel Crafts alkylation.

Highly enantioenriched 2,2-diarylethanols e.g., I were efficiently synthesized through the Friedel-Crafts alkylation of (hetero)arenes with configurationally labile α-bromoarylacetates. The substitution of highly diastereoenriched α-bromoarylacetates occurred in the presence of AgOTf, and the subsequent reduction afforded diverse 2,2-diarylethanols with high yields and enantioselectivities up to 99:1 er. In addition, the application of this asym. synthetic methodol. to the preparation of highly enantioenriched dihydrobenzofuran and indoline derivatives was demonstrated.

Organic & Biomolecular Chemistry published new progress about Benzofurans Role: SPN (Synthetic Preparation), PREP (Preparation) (dihydro). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Product Details of C8H10O2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem