Zhang, Ming-Zhong published the artcileSynthesis of hydroxyl-containing oxindoles and 3,4-dihydroquinolin-2-ones through Oxone-mediated cascade arylhydroxylation of activated alkenes, Related Products of isoquinoline, the main research area is phenyl acrylamide Oxone promoter regioselective tandem arylhydroxylation green chem; hydroxymethyl oxindole preparation; alkenylamido benzene Oxone diastereoselective regioselective tandem arylhydroxylation green chem; hydroxy dihydroquinolinone preparation.
Herein, the first Oxone-mediated direct arylhydroxylation of activated alkenes were developed for the synthesis of valuable hydroxyl-containing oxindoles and 3,4-dihydroquinolin-2-ones. The products were controlled by adjusting the structure of the initial alkenes. Moreover, the reaction were performed under simple conditions without any external additives or catalysts. Primary mechanistic studies showed that this reaction were a tandem process involving epoxidation and subsequent Friedel-Crafts alkylation, and oxone played a dual role (both the oxidant and proton source) in this process.
Green Chemistry published new progress about Alcohols Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Related Products of isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem