Zhang, Qi published the artcileCatalytic Asymmetric Disulfuration by a Chiral Bulky Three-Component Lewis Acid-Base, Application In Synthesis of 1205-17-0, the main research area is dicarbonyl disulfide methoxy Lewis acid base asym disulfuration; disulfide keto stereoselective preparation; chiral primary amines; disulfuration; enamines; frustrated Lewis pairs; organocatalysis.
A three-component Lewis acid-base (Lewis trio) involving a bulky chiral primary amine, B(C6F5)3 and a bulky tertiary amine has been developed as an effective enamine catalyst for enantioselective disulfuration reactions. The bulky tertiary amine was found to activate a bulky primary-tertiary diamine-borane Lewis pair for enamine catalysis via frustrated interaction. The resulted chiral bulky Lewis trio (BLT) allows for the construction of chiral disulfides via direct disulfuration with β-ketocarbonyls or α-branched aldehydes in a practical and highly stereocontrolled manner.
Angewandte Chemie, International Edition published new progress about Enamines Role: CAT (Catalyst Use), SPN (Synthetic Preparation), USES (Uses), PREP (Preparation). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Application In Synthesis of 1205-17-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem