Zhen, Xiaohua’s team published research in Organic Letters in 2019-02-15 | CAS: 5961-59-1

Organic Letters published new progress about Oxidative cyclization. 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Quality Control of 5961-59-1.

Zhen, Xiaohua published the artcileSynthesis of Spirooxindoles from N-Arylamide Derivatives via Oxidative C(sp2)-C(sp3) Bond Formation Mediated by PhI(OMe)2 Generated in Situ, Quality Control of 5961-59-1, the main research area is arylamide oxidative cyclization bond formation dimethoxyiodobenzene; synthesis spirooxindole.

A class of novel spirooxindole compounds I [R = H, Me, OMe, etc.; R1 = Me, iPr, Bu, etc.; X = O, CH2] were readily synthesized, in a metal-free environment, from N-arylamide derivatives II via intramol. oxidative cyclization. Direct oxidative C(sp2)-C(sp3) bond formation was realized with the least-studied PhI(OMe)2 as an oxidant, formed in situ from the reaction between PhIO and MeOH.

Organic Letters published new progress about Oxidative cyclization. 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Quality Control of 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem