Abubshait, Samar A. published the artcileSPIONs as a nanomagnetic catalyst for the synthesis and anti-microbial activity of 2-aminothiazoles derivatives, Category: isoquinoline, the main research area is superparamagnetic iron oxide nanoparticle preparation; thiazolyl aryl methanimine preparation.
A series of aminothiazole derivatives had been synthesized by using ultrasmall superparamagnetic iron oxide nanoparticles (SPIONs) nanomagnetic catalysis, which were prepared by reducing the Fe(II) and Fe(III) precursors using aqueous ammonia then characterized by the XRD, FTIR, SEM, and TEM. The 2-aminothiazole derivatives I [R1 = 3-methyl-5-oxo-1,4-dihydropyrazol-4-yl, 3,5-dimethyl-4H-pyrazol-4-yl, 3-amino-5-oxo-1,4-dihydropyrazol-4-yl] were obtained by coupling 2-aminothiazole diazonium salt with active methylene compounds then cyclization with hydrazine hydrate to afford pyrazolyl derivatives The one-pot reaction of 2-aminothiazole with an aromatic aldehydes in the presence of Fe3O4 NPs to gave Schiff bases derivatives II [Ar = Ph, 4-ClC6H4, 2-OMeC6H4, etc.]. An efficient protocol was developed proudest yields and reduction reaction time and easy separation Therefore, all synthesized compounds I, II were evaluated for anti-microbial activity.
Arabian Journal of Chemistry published new progress about Active methylene compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Category: isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem