Ji, Wangqin published the artcileCopper-catalyzed cyclization reaction: synthesis of trifluoromethylated indolinyl ketones, Quality Control of 5961-59-1, the main research area is aryl fluorobutenone alkylaniline copper catalyst diastereoselective cyclization; aroyl fluoroalkyl alkylindole preparation.
A novel, simple, effective and rapid synthetic method to construct the C-2 trifluoromethylated indolinyl ketones via a copper-catalyzed cyclization reaction between N-alkylanilines and β-(trifluoromethyl)-α,β-unsaturated enones was developed. The results of the control experiments showed that the reaction may involve a radical mechanism by a single-electron transfer process. Moreover, a broad substrate scope and good functional groups, high diastereoselectivities (dr, up to >20 : 1) as well as gram-scale synthesis make this approach highly attractive.
Chemical Communications (Cambridge, United Kingdom) published new progress about Aryl ketones Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Quality Control of 5961-59-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem