Jamil, A. R. Md. published the artcileN-Methylation of amines and nitroarenes with methanol using heterogeneous platinum catalysts, HPLC of Formula: 5961-59-1, the main research area is amine nitroarene methylation methanol heterogeneous platinum catalysis.
Herein the selective N-methylation of amines and nitroarenes with methanol under basic conditions using carbon-supported Pt nanoparticles (Pt/C) as a heterogeneous catalyst was reported. This method is widely applicable to four types of N-methylation reactions: (1) N,N-dimethylation of aliphatic amines under N2, (2) N-monomethylation of aliphatic amines under 40 bar H2, (3) N-monomethylation of aromatic amines under N2, and (4) tandem synthesis of N-Me anilines from nitroarenes and methanol under 2 bar H2. All these reactions under the same catalytic system showed high yields of the corresponding methylamines for a wide range of substrates, high turnover number (TON), and good catalyst reusability. Mechanistic studies suggested that the reaction proceeded via a borrowing hydrogen methodol. Kinetic results combined with d. functional theory (DFT) calculations revealed that the high performance of Pt/C was ascribed to the moderate metal-hydrogen bond strength of Pt.
Journal of Catalysis published new progress about Aliphatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, HPLC of Formula: 5961-59-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem