Mills, L. Reginald published the artcileNi-Catalyzed β-Alkylation of Cyclopropanol-Derived Homoenolates, HPLC of Formula: 151-10-0, the main research area is alkyl ketone preparation; cyclopropanol hydroxyphthalimide ester alkylation nickel catalyst.
Metal homoenolates are valuable synthetic intermediates which provide access to β-functionalized ketones. In this report, a Ni-catalyzed β-alkylation reaction of cyclopropanol-derived homoenolates using redox-active N-hydroxyphthalimide (NHPI) esters as the alkylating reagents has been disclosed. The reaction is compatible with 1°, 2°, and 3° NHPI esters. Mechanistic studies imply radical activation of the NHPI ester and 2e β-carbon elimination occurring on the cyclopropanol.
Organic Letters published new progress about Alkyl aryl ketones Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, HPLC of Formula: 151-10-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem