Nguyen, Khang X.’s team published research in Synlett in 2020-07-31 | CAS: 104-01-8

Synlett published new progress about Aliphatic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Safety of 4-Methoxyphenylacetic acid.

Nguyen, Khang X. published the artcileSulfur-Mediated Decarboxylative Coupling of 2-Nitrobenzyl Alcohols and Arylacetic Acids, Safety of 4-Methoxyphenylacetic acid, the main research area is nitro benzylalc arylacetic acid sulfur mediated decarboxylative coupling; aryl quinazoline.

A new method for the synthesis of substituted quinazolines by the condensation of 2-nitrobenzyl alcs. with arylacetic acids. The transformation requires the use of urea as a nitrogen source, elemental sulfur as a promoter, DABCO as a base and DMSO as a solvent. Functionalities such as chloro, fluoro, trifluoromethyl, thienyl and indolyl groups were all compatible with the reaction conditions. Because this method uses stable simple substrates to obtain the N,N-heterocycles in the absence of transition metals, it offers a potential pathway for preparing complex structures under mild conditions.

Synlett published new progress about Aliphatic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Safety of 4-Methoxyphenylacetic acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem