Ran, Chuan-Kun published the artcileVisible-Light Photoredox-Catalyzed Carboxylation of Activated C(sp3)-O Bonds with CO2, Related Products of isoquinoline, the main research area is carboxylic acid preparation green chem; benzyl alc carbon dioxide photochem carboxylation tetrakis diphenylaminoisophthalonitrile catalyst; benzylic carbonate carbon dioxide photochem carboxylation tris diphenylaminodifluorobenzonitrile catalyst.
A visible-light photoredox-catalyzed carboxylation of activated C(sp3)-O bonds with CO2 under mild and transition-metal-free conditions was reported. A variety of benzyl alcs. and derivatives, RCH(R1)OR2 (R = 4-phenylphenyl, 6-methoxynaphthalen-2-yl, 1-benzofuran-2-yl, etc.; R1 = H, Me, cyclohexyl, propan-2-yl, etc.; R2 = H, Piv, Ac) bearing primary, secondary, and more challenging tertiary C(sp3)-O bonds, undergo carboxylation with CO2, generating valuable aryl acetic acids RCH(R1)COOH, such as ibuprofen, naproxen, fenoprofen, and flurbiprofen, with broad substrate scope and good functional group tolerance. Moreover, this strategy is also applicable to other carboxylates of α-hydroxyl amides, esters, and nitriles, as well as allyl alcs., representing a practical method for aliphatic carboxylic acid synthesis.
ACS Catalysis published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Related Products of isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem