Campano, Teresa E. published the artcileEnantioselective Addition of Alkynyl Ketones to Nitroolefins Assisted by Bronsted Base/H-Bonding Catalysis, Application of 4-Methoxyphenylacetic acid, the main research area is nitro alkynone preparation diastereoselective enantioselective; alkynyl ketone nitroolefin conjugate addition bifunctional bronsted base catalyst; Brønsted bases; Michael reaction; alkynyl ketones; asymmetric catalysis; organocatalysis.
Various sets of enolizable alkynyl ketones (including Me ynones with α-aryl, α-alkenyl and α-alkoxy groups) were able to react smoothly with nitroolefins with the assistance of bifunctional Bronsted base/H-bond catalysts to provide nitro alkynones with two consecutive tertiary stereocenters I [R1 = Ph, 4-MeC6H4, 4-ClC6H4, etc.; R2 = n-Pr, Ph, 2-furyl, etc.; R3 = MeC=CH2, HC=CHPh, Ph, OBn, etc.] in a highly diastereo- and enantioselective fashion. Further transformation of the obtained adducts into optically active acyclic and polycyclic mols., including some with intricate carbon skeletons, was also demonstrated.
Chemistry – A European Journal published new progress about Alkenes, nitro Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Application of 4-Methoxyphenylacetic acid.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem