Demidoff, Felipe C. published the artcileCross-Coupling Reactions with 2-Amino-/Acetylamino-Substituted 3-Iodo-1,4-naphthoquinones: Convenient Synthesis of Novel Alkenyl- and Alkynylnaphthoquinones and Derivatives, Formula: C9H10O3, the main research area is styryl naphthoquinone green preparation diastereoselective; amino iodo naphthoquinone styrene Heck palladium catalyst; alkynyl naphthoquinone preparation; acetylamino iodo naphthoquinone alkyne cross coupling copper mediated; triazole naphthoquinone hybrid preparation; alkyne azide click.
The applications of 2-amino-/acetylamino-substituted 3-iodo-1,4-naphthoquinones in cross-coupling reactions were described to successfully afford sixteen novel 3-styryl-1,4-naphthoquinones (amino-stilbene-quinone hybrids) I [R = Ph, 4-MeC6H4, 1,3-benzodioxol-5-yl, etc.] and four 3-alkynyl-1,4-naphthoquinones II [R1 = TMS, CH2OH, 4-MeOC6H4OCH2, 4-ClC6H4OCH2] in overall good yields. Interestingly, the alkynylated derivatives could be obtained from ligand- and Pd-free CuI-mediated cross-coupling reactions, after extensive investigations to exclude Pd as a co-catalyst. Lastly, the desilanized terminal alkyne was subjected to click chem. reactions to gave two novel triazole-1,4-naphthoquinone hybrids III [R2 = H, OMe].
Synthesis published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Formula: C9H10O3.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem