Devi, Lagudu published the artcileA rapid, sustainable and environmental friendly protocol for the catalyst-free synthesis of 2-methyl-5-oxo-hexahydroquinoline-3-carboxylate via ultrasonic irradiation, Application In Synthesis of 86-51-1, the main research area is methyl oxo hexahydroquinoline carboxylate green preparation ultrasonic irradiation; benzaldehyde cyclohexanedione benzyl acetoacetate multicomponent.
A facile, economic, highly valuable and sustainable protocol for the synthesis of substituted 2-methyl-5-oxo-hexahydroquinoline-3-carboxylate derivatives I [R = 2-FC6H4, 2-BrC6H4, 4-N(Me)2C6H4, etc.] was developed via one-pot, the multicomponent reaction of various benzaldehydes, 1,3-cyclohexanedione, benzyl acetoacetate and ammonium acetate in EtOH under ultrasound irradiation at room temperature condition. Employment of green solvent and catalyst-free conditions made this approach very fascinating from cost-effective and eco-friendly viewpoints. Mainly, this protocol offered various benefits such as easy handling, cleaner reaction, operational simplicity, simple work-up system, excellent yields (92-98%), rapid reaction time and condensed environmental consequences.
Chemical Data Collections published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Application In Synthesis of 86-51-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem