Massaro, Luca published the artcileStereodivergent Synthesis of Trisubstituted: Direct Access to Both Pure Geometrical Isomers, Category: isoquinoline, the main research area is enamide stereodivergent preparation geometrical isomer.
A stereodivergent strategy was developed to access either (E)- or (Z)-isomers of trisubstituted enamides. Starting from an extensive range of ketones, it was possible to synthesize and isolate the desired pure isomer by switching the reaction conditions. Lewis acid activation enables the formation of the (E)-isomers in high stereoselectivity (>90:10) and good yields. However, the use of a Bronsted acid gave the (Z)-isomers, again in high selectivity (up to 99:1), with moderate yields.
Journal of Organic Chemistry published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Category: isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem