Kaper, Tobias published the artcileHydroaminoalkylation/Buchwald-Hartwig amination sequences for the synthesis of benzo-annulated seven-membered nitrogen heterocycles, Computed Properties of 5961-59-1, the main research area is alkene bromophenyl amine titanium hydroaminoalkylation catalyst; aminoalkyl bromobenzene preparation palladium Buchwald Hartwig amination catalyst; azepane preparation.
Reaction sequences consisting of an initial intermol. titanium-catalyzed hydroaminoalkylation of a suitably ortho-bromophenyl-substituted alkene and a subsequent intramol. Buchwald-Hartwig amination are used for the synthesis of benzazepine, benzoxazepine, and benzothiazepine derivatives While in the latter two cases, the hydroaminoalkylation products obtained from an allyl (2-bromophenyl) ether or an allyl (2-bromophenyl) thioether must be purified prior to the subsequent palladium-catalyzed amination step, both reactions can be combined to an efficient one-pot procedure for the synthesis of 2,3,4,5-tetrahydrobenzo[b]azepines when 4-(2-bromophenyl)-1-butene and various N-methylanilines are used as the starting materials.
Tetrahedron published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Computed Properties of 5961-59-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem