Mao, Runze published the artcileDeoxygenative trifluoromethylthiolation of carboxylic acids, COA of Formula: C9H10O3, the main research area is trifluoromethyl thioester preparation; carboxylic acid trifluoromethylthiolating reagent deoxygenative trifluoromethylthiolation Lewis acid catalyst.
A deoxygenative trifluoromethylthiolation method yielded trifluoromethyl thioesters RCOSCF3 [R = 4-t-BuC6H4, 3-MeOC6H4, (2-(2,3-dimethoxyphenyl)vinyl), etc.] from readily available carboxylic acids using trifluoromethylthiolating reagents was repored. The method was built upon an “”umpolung”” strategy where triphenylphosphine was used to first activate an electrophilic trifluoromethylthiolating reagent and then served as an oxygen acceptor for the deoxygenation. The method was mild, efficient, broad-scope and tolerant. The trifluoromethyl thioesters could be converted into trifluoromethyl thioether by Pd-catalyzed decarbonylation.
Chemical Science published new progress about Acids Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, COA of Formula: C9H10O3.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem