Nakano, Ryuhta’s team published research in Tetrahedron in 2020-06-12 | CAS: 151-10-0

Tetrahedron published new progress about 1,3-Dipolar cycloaddition reaction. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Product Details of C8H10O2.

Nakano, Ryuhta published the artcileEfficient transformation of electron-rich arenes into diethyl 3-arylisoxazole-4,5-dicarboxylates, Product Details of C8H10O2, the main research area is arene hydroxylamine hydrochloride acetylenedicarboxylate Vilsmeier reaction dipolar cycloaddition; arylisoxazole dicarboxylate regioselective preparation.

Treatment of electron-rich arenes with Tf2O and DMF, followed by the reaction with NH2OH·HCl and then with oxone in the presence of di-Et acetylenedicarboxylate generated di-Et 3-arylisoxazole-4,5-dicarboxylates in good to moderate yields. Other alkynes could be also used for the present one-pot transformation of arenes into 3-arylisoxazole derivatives

Tetrahedron published new progress about 1,3-Dipolar cycloaddition reaction. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Product Details of C8H10O2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem