Tran, Ngoc Han published the artcileSimultaneous determination of PPCPs, EDCs, and artificial sweeteners in environmental water samples using a single-step SPE coupled with HPLC-MS/MS and isotope dilution, Category: isoquinoline, the main research area is simultaneous determination personal care product endocrine disrupting chem sweetener; personal care product endocrine disrupting chems artificial sweetener determination; solid phase extraction coupled HPLC mass spectrometry isotope dilution; water analysis solid phase extraction HPLC mass spectrometry isotope.
A high-throughput method for the simultaneous determination of 24 pharmaceuticals and personal care products (PPCPs), endocrine disrupting chems. (EDCs) and artificial sweeteners (ASs) was developed. The method was based on a single-step solid phase extraction (SPE) coupled with high performance liquid chromatog.-tandem mass spectrometry (HPLC-MS/MS) and isotope dilution A single-step SPE procedure was optimized for simultaneous extraction of all target analytes. Good recoveries (≥70%) were observed for all target analytes when extraction was performed using Chromabond HR-X (500 mg, 6 mL) cartridges under acidic condition (pH 2). HPLC-MS/MS parameters were optimized for the simultaneous anal. of 24 PPCPs, EDCs and ASs in a single injection. Quantification was performed using 13 isotopically labeled internal standards (ILIS), which allows correcting efficiently the loss of the analytes during SPE procedure, matrix effects during HPLC-MS/MS and fluctuation in MS/MS signal intensity due to instrument. Method quantification limit (MQL) for most of the target analytes was <10 ng/L in all water samples. The method was applied for the simultaneous determination of PPCPs, EDCs and ASs in raw wastewater, surface water and groundwater from a local catchment area in Singapore. The method provided a valuable tool for investigating the occurrence, behavior, transport, and the fate of PPCPs, EDCs and ASs in the aquatic environment. Talanta published new progress about Cosmetics and Personal care products. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Category: isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem