Hennessy, Edward J. published the artcilePreparation of highly functionalized 1,5-disubstituted tetrazoles via palladium-catalyzed Suzuki coupling, Category: isoquinoline, the publication is Tetrahedron Letters (2017), 58(17), 1709-1713, database is CAplus.
The preparation of a range of 1,5-disubstituted tetrazoles has been achieved through palladium-catalyzed Suzuki coupling. Using appropriately substituted 5-p-toluenesulfonyltetrazoles as substrates (obtained by cycloaddition of a substituted azide with p-toluenesulfonyl cyanide), this methodol. provides access to a variety of highly substituted tetrazoles that would be difficult to access otherwise [e.g., 1-phenethyl-5-tosyltetrazole + (4-fluorophenyl)boronic acid â?I (94%) in presence of potassium carbonate, RuPhos and palladium(II) acetate in 1,4-dioxane/water]. The procedure is compatible with functional groups commonly found in drug-like mols., and has been used to generate a number of compounds of potential biol. interest.
Tetrahedron Letters published new progress about 371766-08-4. 371766-08-4 belongs to isoquinoline, auxiliary class Isoquinoline,Boronic acid and ester,Boronic Acids,Boronic acid and ester, name is Isoquinolin-5-ylboronic acid, and the molecular formula is C9H8BNO2, Category: isoquinoline.
Referemce:
https://en.wikipedia.org/wiki/Isoquinoline,
Isoquinoline | C9H7N – PubChem