Simchen, Gerhard et al. published their research in Justus Liebigs Annalen der Chemie in 1975 | CAS: 55086-31-2

1-Chloro-6-methoxyisoquinolin-3(2H)-one (cas: 55086-31-2) belongs to isoquinoline derivatives. Although isoquinoline derivatives can be synthesized by several methods, relatively few direct methods deliver the unsubstituted isoquinoline. The Pomeranz–Fritsch reaction provides a method for the preparation of isoquinoline. This reaction uses a benzaldehyde and aminoacetoaldehyde diethyl acetal, which in an acid medium react to form isoquinoline.Related Products of 55086-31-2

Synthesis and structure of 3-isoquinolinols was written by Simchen, Gerhard;Haefner, Manfred. And the article was included in Justus Liebigs Annalen der Chemie in 1975.Related Products of 55086-31-2 The following contents are mentioned in the article:

The isoquinolinols I (X = Cl, Br, or iodine; R = H, Cl, Br, Me, or OMe; R1 = H, Me, or OMe) were prepared by cyclization of 3,4,6-RR1(NC)C6H2CH2COCl in the presence of anhydrous HX. Hydrogenation of I over Pd/C gave I (X = H). The lactam-lactim tautomerism of these compounds was discussed. This study involved multiple reactions and reactants, such as 1-Chloro-6-methoxyisoquinolin-3(2H)-one (cas: 55086-31-2Related Products of 55086-31-2).

1-Chloro-6-methoxyisoquinolin-3(2H)-one (cas: 55086-31-2) belongs to isoquinoline derivatives. Although isoquinoline derivatives can be synthesized by several methods, relatively few direct methods deliver the unsubstituted isoquinoline. The Pomeranz–Fritsch reaction provides a method for the preparation of isoquinoline. This reaction uses a benzaldehyde and aminoacetoaldehyde diethyl acetal, which in an acid medium react to form isoquinoline.Related Products of 55086-31-2

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem