Bakibaev, Abdigali A. published the artcileSynthesis of glycolurils and hydantoins by reaction of urea and 1, 2-dicarbonyl compounds using etidronic acid as a “”green catalyst””, Formula: C2H6N2O, the main research area is glycoluril green preparation; hydantoin green preparation; urea dicarbonyl compound condensation etidronic acid catalyst.
A new, rather simple and efficient method for the synthesis of a number of glycoluryls I [R1 = H, Me; R2 = H, Me; R3 = H, Me, Ph; R4 = H, Me, Ph] and hydantoins II [R5 = H, Me] in water using a etidronic acid (HEDP) as green catalyst was developed. So, for the first time, the condensation reaction of ureas with 1,2-dicarbonyl compounds was carried out in the presence of HEDP. Also based on NMR studies, a chemism of these reactions, which is stepwise, was proposed. The remaining aqueous filtrate containing HEDP after the reaction could be reused for other cycles synthesis of glycoluril and other compounds, because HEDP was not converted during the reaction.
Journal of Heterocyclic Chemistry published new progress about Condensation reaction. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Formula: C2H6N2O.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem