Jia, Jianhui published the artcileSelf-assembled core-shell clusters in deep eutectic solvents based on tetra-n-alkylammonium cations for high dissolution of strongly hydrogen-bonded small molecules, Synthetic Route of 598-50-5, the main research area is hydrogen bonded compound deep eutectic solvent self assembly; Core–shell clusters; Deep eutectic solvents; High dissolution; Strong hydrogen bonds; TATB.
Strongly hydrogen-bonded compounds such as 1,3,5-triamino-2,4,6-trinitrobenzene (TATB, an important insensitive high explosive) have excellent stability, but poor solubilities to limit their recrystallization, purification and recycling. In this study, core-shell clusters based on sym. tetra-n-alkylammonium [TTA]+ are designed to provide an inner cavity to incorporate TATB, and thus the clusters can sep. TATB from original hydrogen-bonded networks to increase largely the solubility Based on this design, deep eutectic solvents (DESs) based on [TTA]+ cations are first developed to yield self-assembled core-shell clusters for solubilizing TATB. Ninety-nine DESs based on [TTA]+ were prepared by combining with halide ions and hydrogen bond donors, and TATB’s solubility increases with the formation of core-shell clusters. Tetra-Bu ammonium ([TBA]+)-based DES (CS-1) displays excellent dissolution toward TATB. Room-temperature solubility of TATB in CS-1 with 32.88 mg/mL is about 10 times higher than recently reported ionic liquids and approx. 470 times higher than DMSO. Compared to traditional solvents, CS-1 shows economical and high dissolution ability toward TATB. The dissolution mechanism is demonstrated by exptl. characterizations and theor. calculations After forming Zundel-type complexes between TATB and F-, the complexes as the core are surrounded by [TBA]+ as the shell to yield core-shell clusters through self-assembly of electrostatic interaction.
Journal of Colloid and Interface Science published new progress about Core-shell materials. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Synthetic Route of 598-50-5.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem