Zott, Fabian L.’s team published research in ChemBioChem in 2022-04-05 | CAS: 598-50-5

ChemBioChem published new progress about Boltzmann constant. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Application of 1-Methylurea.

Zott, Fabian L. published the artcileThe pH-Dependence of the Hydration of 5-Formylcytosine: an Experimental and Theoretical Study, Application of 1-Methylurea, the main research area is formylcytosine hydration hydrogen ion concentration; DNA methylation; TET enzymes; aldehyde hydrates; computational chemistry; epigenetics; modified nucleic acids.

5-Formylcytosine is an important nucleobase in epigenetic regulation, whose hydrate form has been implicated in the formation of 5-carboxycytosine as well as oligonucleotide binding events. The hydrate content of 5-formylcytosine and its uracil derivative has now been quantified using a combination of NMR and mass spectroscopic measurements as well as theor. studies. Small amounts of hydrate can be identified for the protonated form of 5-formylcytosine and for neutral 5-formyluracil. For neutral 5-formylcytosine, however, direct detection of the hydrate was not possible due to its very low abundance. This is in full agreement with theor. estimates

ChemBioChem published new progress about Boltzmann constant. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Application of 1-Methylurea.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem