Kumar, Naresh published the artcileAnti-oxidation properties of 2-substituted furan derivatives: A mechanistic study, HPLC of Formula: 104-01-8, the main research area is furan derivative absorption antioxidant property.
2-(P-Ph substituted styryl)-furans were synthesized and studied the excited state and anti oxidation properties using absorption, fluorescence, d. functional theory and DPPH radical scavenging assay. 2-(P-hydroxy Ph styryl)-furan (6) exhibits good antioxidant properties with IC50 â?40μM as compared to the amine, chloro, cyano methoxy and nitro substituted styryl compounds (1-5, 7-8) (IC50 > 150μM). It is shown that furans 1-3 with strong electron withdrawing nitro, cyano and chloro substituent do not show antioxidant properties. The O-H bond dissociation energy (BDE) of p-hydroxy substituted furan compound is comparable to the BDE of vitamin E. The antioxidant activity of furan compound is further reduced with increasing the dipolar nature of the mol. From the thermodn. parameters and antioxidant properties, it is shown that there is a correlation of antioxidant properties with the ground state dipole moment, X-H bond dissociation energy (X: O; N) and proton affinity (PA). In presence of the furan compound, the quenching of DPPH radical is occurred predominantly through hydrogen atom transfer mechanism.
Journal of Luminescence published new progress about Antioxidants. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, HPLC of Formula: 104-01-8.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem