Syntheses and antifilarial profile of 5-amino and 5,8-diaminoisoquinoline derivatives: a new class of antifilarial agents. [Erratum to document cited in CA126:84084] was written by Srivastava, Sanjay K.;Chauhan, P. M. S.;Agarwal, S. K.;Bhaduri, A. P.;Singh, S. N.;Fatma, Nigar;Chatterjee, R. K.;Bose, Chhanda;Srivastava, V. M. L.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 1997.COA of Formula: C9H5BrN2O2 This article mentions the following:
Structures 4 and 7 are corrected The structures and other materials of 10, 11 and 12 are omitted. Reagent (III) is corrected to propylene oxide. The spectroscopic data for 4 and 7 are corrected In the experiment, the researchers used many compounds, for example, 5-Bromo-8-nitroisoquinoline (cas: 63927-23-1COA of Formula: C9H5BrN2O2).
5-Bromo-8-nitroisoquinoline (cas: 63927-23-1) belongs to isoquinoline derivatives. Isoquinoline is a structural isomer of quinoline, which have antiseptic, antipyretic and anti-cyclic properties, and can be used as antimalarial drugs and for the preparation of other antimalarial medicine. The Pomeranz鈥揊ritsch reaction provides a method for the preparation of isoquinoline. This reaction uses a benzaldehyde and aminoacetoaldehyde diethyl acetal, which in an acid medium react to form isoquinoline.COA of Formula: C9H5BrN2O2
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem