Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 4-Bromoisoquinoline, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 1532-97-4
Some ethers, such as cyclopentyl methyl ether and di-n-butyl ether, which can be considered as “greener” solvents than N,N-dimethylacetamide (DMAc) or DMF, can be advantageously employed for the palladium-catalyzed direct arylation of heteroaromatics. In the presence of such ethers and only 0.5-1 mol% of palladium catalysts at 125-150C, the direct 5-arylation of thiazoles, thiophenes, or furans by using aryl bromides as coupling partners proceeds in moderate to high yields.
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Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H3030N – PubChem