724422-42-8, 6-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,724422-42-8
To a solution of compound 64.3 (0.25 g, 1.04 mmol, 1.0 eq) in toluene (1.0 mL) was added benzophenonimine (0.21 g, 1.14 mmol, 1.1 eq) and NaOBut (0.15 g, 1.56 mmol, 1.5 eq). The mixture was degassed for 10 minutes using argon, then Pd2(dba)3 (0.009 g, 0.01 mmol, 0.01 eq) and BINAP (0.029 g, 0.052 mmol, 0.05 eq) were added. The reaction was then heated at 100 C. for 8 hours. After completion, reaction mixture was poured into water and product was extracted with EtOAc. Organic layers were combined, washed with brine, dried over Na2SO4 and concentrated under reduced pressure to obtain crude material. The crude was purified by column chromatography to provide 64.4 (0.04 g, 21.8%). MS(ES): m/z 176.22 [M+H]+.
As the paragraph descriping shows that 724422-42-8 is playing an increasingly important role.
Reference：
Patent; Nimbus Lakshmi, Inc.; Dahlgren, Markus; Greenwood, Jeremy Robert; Harriman, Geraldine C.; Kennedy-Smith, Joshua Jahmil; Masse, Craig E.; Romero, Donna L.; Shelley, Mee; Wester, Ronald T.; (131 pag.)US2016/251376; (2016); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem